Our Metabolic Health theme supports interdisciplinary research that aims to understand the molecular and physiological basis of healthy resilience and how this ultimately deteriorates in response to ageing and the environment to drive disease. It will tackle some of the world’s most urgent health challenges by harnessing expertise in molecular metabolism, neurodegeneration, anti-microbial resistance and cancer biology.

This theme enables a collaborative research ideology to generate answers to urgent questions and benefit our understanding of human health. Researchers investigate cellular and physiological mechanisms to identify underlying fundamental disease processes and, leverage this approach to seek new therapeutic tools. As collaborative teams, harnessing inter- and transdisciplinary approaches our members strive to understand how health is maintained against environmental and genetic insults and to detect the earliest signs of disease when our natural resilience is overcome. This approach aids the development of new investigations, treatments, and management strategies and exploits state-of-the-art technological platforms.